YK11 SARM Benefits, Results and Side Effects

What Is YK11 SARM – How to Use It to Get Results and Avoid Side Effects

24 min read

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20 Mar 2024

What Is YK11 SARM – How to Use It to Get Results and Avoid Side Effects

What is YK11 SARM?

If some users are to be believed, then YK11 is not your average SARM. Far from it. Many would describe it as a ‘super SARM’ because of its SARM-steroid hybrid status.

Alongside promising users that it can help them to reach their full physical and mental potential – with none of the nasty side effects (supposedly) – YK11 SARM can also stimulate quick muscle gains, bolster fat loss, and improve bone health.

The Science Behind YK11

The truth is, YK11 is a synthetic steroid that has been created by directly altering the chemical structure of DHT (a hormone that occurs naturally in the body) – a stronger form of testosterone. This alteration places YK11 among anabolic-androgenic steroids (AAS). Steroid hormones like testosterone and progesterone have similar structural backbones, and YK11's structure aligns closely with these, explaining its classification as an AAS.

However, YK11 is also considered a selective androgen receptor modulator (SARM) because it acts as a partial agonist of the androgen receptor (AR). This means it binds selectively to ARs, specifically in muscle and bone tissues, which is the hallmark of SARMs. This selective binding is thought to help enhance muscle mass and bone density, while potentially minimizing side effects typically associated with steroids, such as male-pattern baldness and acne.

Theories and Effects

Now here is where things get tricky because there are multiple theories surrounding YK11 SARM.

  1. Myostatin Inhibition: One theory suggests YK11 acts as a myostatin inhibitor. This theory arose following a cellular study where YK11 was found to increase muscle mass by boosting the growth of follistatin, an essential muscle-building protein known to inhibit myostatin.

  2. SARM Characteristics: Another perspective emphasizes that YK11 is a powerful SARM. This is based on studies showing YK11's ability to stimulate bone-building proteins and selectively bind with androgen receptors in bones and muscles, enhancing lean muscle mass and bone density.

Clarifying the Dual Classification

The dual classification of YK11 as both an AAS and a SARM is partly due to the lack of strict regulatory definitions distinguishing the two. The term "SARM" often lacks a precise boundary, leaving room for compounds like YK11 to be considered as hybrids. As research progresses, the lines between these categories may become clearer, offering more definitive insights into YK11’s potential uses and benefits.

By focusing purely on the androgen receptors in muscle and bone, YK11 may offer a targeted approach to muscle growth and bone strengthening, aligning with the overarching goals of users seeking enhanced physical performance without the full spectrum of side effects associated with traditional steroids.

Selective Activation

YK11 shows the ability to selectively activate androgen receptors, albeit modestly. This selective activation could potentially minimize side effects associated with androgen therapy.

Potential Benefits over Traditional Options

  • Reduced Side Effects: Traditional androgen therapies often come with significant side effects. YK11's selective action on receptors suggests it could provide similar benefits with less risk.
  • Targeted Action: While it doesn’t match the receptor selectivity of other Selective Androgen Receptor Modulators (SARMs), its focused action is still of great interest for its possible advantages in therapeutic settings.

Research Implications

With these appealing characteristics, YK11 stands out as a promising candidate for further exploration in the quest to develop more effective and safer treatments. Researchers continue to delve into its mechanism to fully understand its potential in medical applications.

Things to consider:

  • So far, the only studies this SARM has seen are cellular ones. No animal ones and no human ones. This means that despite all the claims surrounding this SARM, there is actually no evidence to back them up, so you need to take their claims with a pinch of salt.

  • Like all SARMs, YK-11 has been banned by the WADA, making it illegal and off-limits to competing bodybuilders and athletes.

  • It's important to note that YK11’s mechanism of action differs significantly from other SARMs. While most SARMs primarily bind to androgen receptors to promote muscle growth, YK11 is uniquely known for its ability to increase follistatin levels, which helps inhibit myostatin activity. As myostatin levels are kept in check, this prevents it from hindering muscle growth or stopping your muscles from getting too large.

  • Remember how we mentioned that YK11 is synthetically altered DHT and that it will only bind to the androgen receptors found in your muscles and bones? Well, alongside triggering natural growth, and encouraging good prostate health and proper development in puberty; YK11 also only activates androgen receptors partially, preventing their full activation. As a result, this limited activation can increase the activity of catabolic androgen genes.

    To grasp YK11's role as a partial agonist, it's essential to understand what an androgen receptor (AR) agonist does. In simple terms, androgens like testosterone and its potent derivative, dihydrotestosterone (DHT), act as primary activators of the AR. They bind to these receptors and trigger crucial processes such as sperm production and muscle growth. However, full activation by DHT can lead to unwanted effects like male-pattern baldness and acne.

    Here's where YK11's partial agonism becomes interesting. As a selective androgen receptor modulator (SARM), YK11 binds selectively and partially to the AR. This selective binding is what sets it apart from DHT, as it aims to trigger essential growth processes without the undesirable side effects. Researchers are particularly interested in YK11's potential as a safer alternative in androgen therapy due to its ability to selectively activate androgen receptors.

    While YK11 shows promise in selectively targeting muscle and bone receptors, it is still not as selective as some other SARMs. However, this unique partial agonism could offer a balance between effectiveness and minimizing side effects, making it a fascinating subject for further scientific exploration.

  • And this is the only SARM known to inhibit myostatin. Which is good news for you, as you’ll be able to enjoy unbridled gains and muscle growth, day after day.

  • With the lack of comprehensive data, both in animals and humans, drawing bold conclusions about YK11 compared to other SARMs remains speculative at best. However, when used as an addition to a performance-enhancing stack, you might leverage its unique properties more effectively.

  • Another positive YK11 result you can look forward to is its ability to affect DHT-like pathways. By activating protein kinase B, this sends signals to your brain to increase the creation of bone-building cells and encourage greater bone growth.

In summary, while YK11 offers intriguing possibilities due to its unique properties, the lack of robust research data makes it crucial to approach its use with caution and consider it more as a supplementary element within a broader performance-enhancing strategy.

Understanding the Current State of YK11's Safety and Effectiveness

YK11, a selective androgen receptor modulator (SARM), remains a topic of debate within the scientific community regarding its safety and effectiveness. Despite its popularity in certain circles, this compound has not received approval for human use. The lack of comprehensive studies leaves many questions unanswered.

Limited Research

  1. Studies Conducted: Research on YK11 has been primarily limited to cellular analyses, with no extensive clinical trials on humans. This scarcity of data means that the full range of potential side effects is not well-documented.

  2. Preliminary Findings: Initial studies do suggest that YK11 might have muscle-building properties, yet these findings are speculative and not sufficiently verified through rigorous scientific methodologies.

Safety Concerns

  • Unknown Long-term Effects: Given that YK11 has not been thoroughly researched, the long-term implications for users remain unknown. The potential for adverse reactions is a significant concern.
  • Regulatory Status: Many health authorities have not sanctioned YK11 for use, indicative of caution due to incomplete safety profiles.

Recommendations

While YK11's potential benefits may appear appealing, the absence of solid scientific backing and approved usage guidelines should be carefully considered. Experts recommend steering clear of untested SARMs, including YK11, until more conclusive research is available. Prioritizing safety over unverified results is crucial for those considering such compounds.

This reflects the current understanding, underscoring the importance of evidence-based decision-making when it comes to supplements and performance enhancers.

How does YK11 work?

Closeup of sporty muscular man arms showing sports and fitness supplements

Remember how we mentioned that YK11 is synthetically altered DHT and that it will only bind to the androgen receptors found in your muscles and bones? Well, alongside triggering natural growth, and encouraging good prostate health and proper development in puberty; YK11 also only activates androgen receptors partially, preventing their full activation. As a result, this limited activation can increase the activity of catabolic androgen genes.

At the same time, YK11 can help inhibit myostatin activity by increasing the presence of follistatin in your body. As these levels rise, this will help to keep your myostatin levels in check and prevent it from hindering muscle growth/stopping your muscles from getting too large.

Follistatin acts as a natural antagonist to myostatin, the protein responsible for limiting muscle growth. By boosting follistatin, YK11 effectively reduces myostatin's muscle-restricting actions, leading to enhanced muscle development.

Research supports this interaction. Studies with follistatin knockout mice—mice without the follistatin gene—showed that the absence of follistatin resulted in significantly lower muscle mass at birth. This is due to the unchecked activity of myostatin, highlighting follistatin's crucial role in muscle regulation.

What's interesting about YK11 is its ability to selectively bind to androgen receptors while promoting follistatin expression—a mechanism distinct from other Selective Androgen Receptor Modulators (SARMs). This dual action not only enhances its effectiveness but also contributes to its classification as both an anabolic steroid and a SARM, making it particularly appealing to those looking to maximize muscle growth.

But what exactly is myostatin, and why is it important to control it? Myostatin is a protein expressed in skeletal muscle that acts as a gatekeeper, limiting the growth of muscle fibers. In conditions like HIV, AIDS, and cancer, myostatin is often overexpressed, contributing to muscle-wasting.

Research dating back to the 1960s speculated on its existence, but it wasn't until 1997 that its role became clear. Studies on mice using a gene knockout model—where the myostatin gene was removed—revealed remarkable increases in muscle mass. These mice developed muscles weighing twice as much as those in the control group, highlighting myostatin's significant impact on muscle development.

Interestingly, the absence of myostatin led to muscle growth through two pathways: hyperplasia (more muscle fibers) and hypertrophy (larger fibers). This dual effect suggests that YK11 opens a new avenue for muscle growth that other SARMs and anabolic agents don't explore.

And this is the only SARM known to inhibit myostatin. Which is good news for you, as you’ll be able to enjoy unbridled gains and muscle growth, day after day.

Furthermore, examples like the Belgian Blue bull, which has a natural mutation in the myostatin gene, demonstrate the potential for increased muscle accretion and reduced fat deposition. At birth, these calves weigh nearly twice as much as normal calves, underscoring the power of myostatin inhibition.

YK11's unique ability to bind to androgen receptors while boosting follistatin sets it apart, offering a distinct edge in your fitness regimen.

Another positive YK11 result you can look forward to is its ability to affect DHT-like pathways. By activating protein kinase B, this sends signals to your brain to increase the creation of bone building cells, and encourage greater bone growth.

YK11 Results – Potential health benefits of YK11

We’ve touched on two of these already. However, to help you get a better idea of how YK11 works; here are its most common health benefits:

  • Increased muscle size

YK-11 may not be a traditional SARM but it can still stimulate muscle growth and produce new muscle cells (by naturally increasing follistatin cells), whilst suppressing myostatin (a protein that stops excessive muscle growth).

  • Numerous users have reported benefiting from 10-15lbs worth of lean muscle mass gains in just one 8 week YK11 cycle.
  • Fat reduction

Alongside encouraging lean muscle mass growth, YK 11 SARM can also cause significant fat losses in a short space of time.

  • Healthier, stronger bones

A key part to keeping your bones healthy is sex hormones. Studies suggest that YK11 can help to improve your bone strength by binding itself to your androgen receptors. It can also increase the level of activated PKB (protein kinase B) in your cells, resulting in bone growth.

  • Increased strength

The idea of strength moves in an endless cycle, namely because they are so intimately entwined. When it comes to increased strength – as you are able to lift more weight; more muscle fibers will be stimulated.

Reported Effects of YK11 According to Recreational Users

When it comes to YK11, recreational users have often highlighted its dual benefits in both muscle-building and muscle-hardening, though the latter effect is less understood. The lack of comprehensive human trials specifically addressing YK11's influence on athletic performance and physique enhancement leaves some mechanisms of action unclear.

Muscle-Hardening Effects

One key attribute reported is the muscle-hardening effect. This could be linked to YK11’s interaction with dihydrotestosterone (DHT), as DHT-derived steroids like trenbolone and stanozolol are renowned for similar outcomes. These substances are typically favored in cutting cycles because they enhance muscle definition without causing the water retention often associated with other anabolic steroids. Users of YK11 have noted similar effects, making it a popular choice for those looking to maintain a leaner appearance.

Ideal Usage Context

YK11 is often preferred during cutting phases rather than bulking. This is due to its limited ability to drastically increase muscle mass, akin to how trenbolone and stanozolol function. Such steroids are not typically expected to result in significant mass gains, which aligns with the experiences of those who use YK11.

Overall, while the precise workings of YK11 are still being unraveled, anecdotal evidence suggests its advantages lie more in refining muscle tone than in building sheer size.

Benefits for bodybuilding

Truthfully, a lot of the above health benefits could easily be applied to bodybuilders.

From stimulating increased lean muscle mass, to boosting fat loss and protecting your bones from density loss and fractures; by taking just 5mg of YK-11 a day (over 4 weeks) you can: gain over 5lbs of lean muscle; increase your chest, arm and calf measurements, and lose 2% body fat.

PLEASE NOTE: this figure is based on the average results of a lot of users.

What makes YK 11 SARM so appealing to bodybuilders is the way that it builds muscles by facilitating follistatin.

By tackling muscle growth in such a unique way; you can escape with little to no side effects and will suffer from only mild testosterone suppression – which can be prevented with good old PCT.

In fact, users state that you will begin seeing muscle mass gains in as little as a week. Plus, it has proven to be beneficial in both bulking and cutting cycles.

Think about it…

This super SARM can technically help you to pile on lean muscle fast (during bulking), whilst helping you to burn fat and harden muscles during a calorie deficit (cutting).

Who can say no to claims like that? It is no wonder it is so popular.

But here is the thing…

It may be able to do all of this (in theory), but there is a massive difference between what happens at a cellular level and what will actually occur in your body. Without human trials/studies to substantiate these bold claims, all they really are, are words. Nothing more.

Hell, even YK11 reviews are not 100% reliable, as these claims are clouded by their varying dosages, Y11 cycles and what they stacked it with.

YK11 side effects

There are some who will swear blind that YK11 SARM doesn’t cause any side effects. But we have to disagree. Sure, a lot of them can be remedied once you stop, and yes, they appear to be temporary. However, we view any negative change to your body as a side effect.

Take a look at the following:

  • It has got a steroidal structure

Making it not your average SARM

  • Testosterone suppression

Users have reported drops in natural testosterone production following a YK11 cycle. Admittedly, it was only temporary and was easily restored with the help of PCT, but we advise you to be cautious.

  • Liver toxicity (maybe)

Whilst most SARMs don’t have to deal with this; due to its hybrid steroid nature – and the fact that at a chemical level it is close to steroids – there have been some reports of it damaging your liver.

True, this hasn’t been fully confirmed but it is easy to see the potential for it.

  • No human/animal studies

We know this isn’t an actual side effect, but it is a BIG con that you need to be aware of. Why? Because all of its claims are based on cellular studies. There is no evidence proving that it can build lean muscle mass and burn fat in real people.

  • Long term risks unknown

And this is another downer to the lack of human studies. It is all based on speculation with no real guarantee that your body isn’t at risk or in danger.

  • Health issues

As YK11 is so strong – and similar to steroids – there is a growing concern that it may affect hair growth, prostate health, the pitch of your voice and other organs. Other health concerns include oesophagus, stomach, skin and prostate cancer (due to too high a follistatin presence); although it has been positively linked to breast cancer.

  • Increased aggression

It might not cause full roid rage, but users have reported feeling angrier, more aggressive and being quicker to react outside of the gym due to it suppressing natural hormone production.

  • Joint pain

This is a common complaint amongst YK11 users.

  • Hair loss and mild acne

Now, most of these are due to a too high a YK11 dosage, so by taking the correct amount you can minimize this risk.

Similarly, all of these side effects are based on user experiences NOT research or clinical studies.

Does this mean they don’t exist? Yes and no. Personally, we feel that they are still a very real possibility, as they are all common side effects of SARMs and anabolic steroids. The proof may be lacking, but the personal experience is there.

Findings from the Myostatin Gene Knockout Study in Mice

In a groundbreaking study, researchers explored the effects of removing the myostatin gene in mice. This genetic alteration led to remarkable increases in the size of skeletal muscles. On average, the muscle mass of mice without the myostatin gene doubled compared to their counterparts in a control group.

Key Observations:

  • Muscle Fiber Proliferation: The increase in muscle mass was attributed to both a rise in the number of muscle fibers, known as hyperplasia, and an enlargement of existing fibers, referred to as hypertrophy.

  • Potential for New Pathways: These results hint at the possibility that altering myostatin could open up additional pathways for muscle growth. This represents a unique opportunity distinct from the effects typically seen with selective androgen receptor modulators (SARMs) or anabolic-androgenic steroids (AAS).

However, it's important to note that these pathways are still hypothetical and have yet to be explored in depth through further research.

YK11 vs. Other SARMs: A Comparison of Side Effects

When comparing YK11 to other Selective Androgen Receptor Modulators (SARMs) such as LGD 4033 and RAD 140, the side effect profile is an important consideration for potential users.

Prominence of Side Effects

YK11 is often noted for having prominent side effects. While these effects can vary in intensity among individuals, some users find YK11's side effects to be similar in nature to those of traditional anabolic steroids. In contrast, LGD 4033 and RAD 140 are generally associated with milder side effects, making them popular choices for those looking to minimize adverse reactions.

Lack of Comprehensive Data

A significant challenge with YK11 is the limited amount of comprehensive research available. This makes it difficult to fully assess the potential long-term side effects, which remain a considerable concern for users. Both LGD 4033 and RAD 140 have been studied more extensively, providing a clearer understanding of their risk profiles.

Regulatory Status

In terms of regulation, all three compounds are banned by the World Anti-Doping Agency (WADA). Despite this, the perception of YK11 often leans more towards that of a synthetic steroid rather than a typical SARM due to its structure and effects.

Conclusion: Choosing Wisely

Ultimately, when evaluating YK11 against LGD 4033 and RAD 140, potential users must weigh the severity of potential side effects against the lack of long-term safety data, and consider their specific fitness goals and risk tolerance. Consulting with a healthcare professional is always recommended before considering the use of any SARMs.

How to use it – YK11 dosage and cycles

With as little as 5mg of YK11 SARM a day (taken over 4-8 weeks), you can begin to see positive muscle gains. However, most YK11 users recommend taking 10-15mg a day. Any more and you risk experiencing more negative side effects.

Common Dosage Recommendations and Challenges

It's important to note that there is no "standard" dose for recreational use. Dosage amounts you may see online are derived anecdotally. While 10-30mg per day seems relatively common, the lower end of this range is much more typical. Most users find it unnecessary to exceed 20mg to observe notable results.

What else do you need to know?

  • Start small: Begin with a lower dose and only increase if you experience no side effects.
  • Cycle One: 5mg of YK11 a day for 6 weeks. NOTE: this cycle is great for newbies.
  • Cycle Two: 10-15mg a day for up to 8 weeks. NOTE: only for experienced users.
  • Female users: Typically take only 0.5-2mg of YK11 a day.

Understanding the Challenges: Establishing a dosing protocol is difficult due to the lack of data on YK11’s bioavailability and half-life. Anecdotal evidence suggests it might be short, similar to other SARMs like LGD-4033, which have a half-life of 24-36 hours. This speculative approach highlights the importance of splitting your YK11 dosage in two to help maximize its presence in your system and keep your blood levels stable.

  • Half-life: While lacking precise research, data from studies aimed at drug testing standardization suggest YK11's metabolites are detectable in urine 36-48 hours after administration. This indicates the need for a consistent dosing schedule to maintain stable blood concentrations.
  • Overdosing Risks: Dosages of 15-30mg are generally considered too much, increasing the risk of adverse side effects.

With these insights, you can better navigate YK11 dosage, balancing potential benefits with the inherent uncertainties due to limited research.

    Post Cycle Therapy

    To ensure you're on the right track, it's highly recommended to complete a PCT after finishing a YK11 cycle. This becomes crucial if you've combined YK11 with other anabolic steroids or SARMs. While human trials are still limited, skipping PCT could lead to low testosterone levels—a risk not worth taking.

    When to Start Your PCT

    Given YK11's estimated half-life of 24-36 hours, you should initiate your PCT the day after your last dose of YK11. Timing is key to optimizing recovery and maintaining hormonal balance.

    Choosing Your PCT

    You have two main options for your PCT: Nolvadex (Tamoxifen) and Clomid (Clomiphene). Either can effectively aid in your recovery. Although Nolvadex is often preferred for its milder effects, Clomid is another viable choice. Rarely will you need to use both simultaneously.

    A Simple 4-Week Protocol

    Here's a straightforward 4-week plan to guide your PCT:

    • Week 1-2

      • Nolvadex: 40 mg/day
      • OR Clomid: 50 mg/day
    • Week 3-4

      • Nolvadex: 20 mg/day
      • OR Clomid: 25 mg/day

    By following this protocol, you can help safeguard your testosterone levels and ensure a smoother transition post-cycle.

    What Are Some Myths Associated with YK11 SARM?

    When it comes to YK11 SARM, there are several myths that tend to circulate. Understanding the facts is crucial for making informed decisions about its use. Let’s debunk some common misconceptions:

    • Undefined Dosage Specifics: Many people believe that there is a universally agreed-upon dosage for YK11. In reality, no definitive dosage guidelines are medically established, and users often rely on anecdotal evidence.

    • Half-Life Ambiguity: Another common myth is regarding YK11's half-life. It's often claimed to have a specific half-life, but the scientific community does not have a consensus on this, leading to varied assumptions.

    • Post Cycle Therapy (PCT) Is Unnecessary: It’s a misconception that YK11 doesn’t require PCT. Like other SARMs, YK11 may suppress natural hormone levels, making PCT an important consideration for users wishing to restore their endocrine function post-cycle.

    • Liver Impact: Lastly, YK11 is sometimes said to be non-toxic to the liver. However, there's insufficient evidence to guarantee its safety in this regard, and it could potentially be hepatotoxic.

    Understanding these myths can help mitigate risks and inform safer use of YK11. Always prioritize credible sources and consult healthcare professionals when considering any supplement or compound.

     

     

    Where to buy YK11

    FACT: Like all SARMs, YK11 is prohibited in professional sports and has been banned by the WADA. Meaning no matter how it has been labelled, it is still illegal and will get you kicked out of competitions.

    FACT TWO: YK-11 can only be bought as a research chemical. This means, yes – it is technically possible to buy this SARM BUT you will need to purchase it from a trusted, reputable and approved source, so you don’t end up with a fake.

    In all honesty, we recommend steering clear of YK11 because any supplement that has been banned cannot be entirely safe for your body. Why take the risk?

    Conclusion

    True, YK11 SARM may be one of the strongest compounds around. And yes, it appears to produce rapid lean muscle gains and fat losses in a short space of time (10-15lb gains during an 8-week cycle). However, this product isn’t entirely risk-free or innocent.

    First, YK11 has never been tested on humans or animals. All of these bold bodybuilding claims are based on cellular studies. There is no real proof that it will work at the level these sites claim it will.

    Despite its promising effects, the question remains: Is YK11 worth using despite its potential side effects? Based on limited research, we think not. The side effects simply aren't worth the risk. So far, only cell-based studies have supported its claims of building muscle via myostatin inhibition, leaving much uncertainty about its true impact.

    Second, it has been banned by the WADA and is prohibited from use in competitions. In other words, it is illegal to buy unless it is for research purposes.

    Now, you might claim that your workout regime is a form of ‘research’. But if you’re serious about bodybuilding and competing, then this SARM CAN and WILL get you kicked out.

    Third, there is no knowledge of its long-term impact.

    Arguably, you could say that with such minimal research, we don’t know for certain that it will cause the side effects already on its list. But given that it is based on the reviews of hundreds if not thousands of users, then there must be an element of truth to it causing acne, baldness, testosterone suppression, and aggression.

    The real concern is – what are its long-term implications, and how closely related to steroids is it? After all, anabolic steroids have got a long history of causing some nasty side effects. If it is truly a hybrid of anabolic steroids, then there is a greater chance of you suffering from these side effects.

    Why take the risk? Why expose yourself to such dangers when there are safer legal and natural alternatives available? You shouldn’t have to.

    What are other safer options for muscle building?

    The bottom line is: genuine SARMS are illegal (unless bought for research purposes only) and are becoming scarcer as the government cracks down.

    So YES, whilst they are safer for your body than steroids, and can produce positive muscle mass gains, fat loss, and recovery (although in a milder form than steroids) – anything you find online won’t be the real deal.

    Far from it!

    If anything, fake SARMs have the potential to be more dangerous than steroids, as who knows what they have put in it!

    That is why, if you want to experience lasting muscle mass gains, we strongly recommend pursuing natural supplementation, such as our latest line; formulated of 6 SAFE and NATURAL SARMSs alternative supplements.

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